The One Codex Blog

As part of our partnership with ATCC, the team at One Codex launched Supporting Memberships for the ATCC Genome Portal earlier this year! In this post we’ll walk through some of the awesome new features and capabilities that Supporting Memberships are bringing to ATCC’s collection of 5000 authenticated microbial genomes. Every quarter ATCC will publish additional genomes.

We just launched a brand new feature that’s been near the top of the list of requests for a while - now when you want to upload FASTQ files from ONT sequencers but each file is split into several parts we’ll automatically detect the parts and concatenate the files together for you!

Genome Library is a new feature that simplifies microbial genomics by offering one-click assembly, user-friendly genome annotation browsing, and real-time querying of genomic sequences, addressing challenges in accessing and utilizing genomic data.

We are constantly looking for new ways to help our users get more out of their data. With many more users exploring Functional Analyses on their samples, we wanted to provide a better way of comparing those results between samples. To kick that mission off, we have now implemented plotting of functional data in our Custom Plots tool!

Sequencing viral genomes from mixed microbial community samples is challenging due to the relatively low quantity of viral reads compared to host and/or background. One Codex and Twist Bioscience have co-developed targeted enrichment-based sequencing and analysis kits for recovery of whole viral genomes from high-background samples¹. This semi-targeted approach enables enrichment of known viruses while still capturing novel viruses.

The Twist Viral Research panels bundled with One Codex analysis are available in two versions. The Twist Respiratory Viral Research panel covers 29 human and respiratory viral pathogens. The larger Twist Comprehensive Viral Research Panel covers 3,153 viral pathogens known to infect both humans and animals². Both versions have been applied across public health, medicine, academia and industry in diverse use cases, such as evaluating wastewater viromes³, characterization of emerging pathogens⁴, discerning the infectious agent in an outbreak⁵, evaluating co-infections⁶, and novel strain detection^{6, 7}.